The ones who once were helpful are now a burden

Hi! I've been through a lot this semester including the intense feeling of being a misfit/ feeling isolated etc. To the extent that Ive started experiencing pain in my right temple whenever I stress out. I can't thank my Friends enough who helped me out of this crisis but now I'm facing another problem: This one person was so helpful during my depression, for which I'm glad. And now I feel extremely terrible when I don't get her attention / validation. Moreover, the relationship isn't that much cheerful as it was in the start. How can I figure myself out?