Depression and job search are a terrible combination. The loss of income and employment makes it really hard to be happy. First, you can identify the kind of work that will make you happy. Even if you don't think you will get a job in that field, just the act of pursuing something you would love can give you the motivation to get cover letters written, resumes completed, references set up, etc. Once you have those done for your "dream jobs", you'll at least have an easier time submitting applications for everything else because you'll already have the documents you need. This will also help work through your depression a bit because you're focusing on things that you want to do. Second, understand that even though "looking for work" is a full time job, like any job, there is a risk of burnout. Don't kid yourself into thinking that you can apply for jobs 12 hours a day, every day. Take breaks. Set realistic goals. Third, make sure you set time aside for normal "after work" activities such as talking with friends, getting their input into your situation, networking, etc. Most often, the best job leads come from people that you know or friends of friends. Put yourself in a position to meet them. Fourth, find places where you can work. When I lost my job, and found myself wasting too much time at home, I began going to Starbucks, and to the library- places where I could more easily focus and get work done. The idea is to get yourself into better environments that are more conducive to getting things done. Fifth, get a part time job, or volunteer. Do something that keeps you active and engaged in the community. Again, you may feel that this is counterproductive to your job search, but it's actually helpful in several ways: it gets you busy, it helps you keep a normal schedule, it helps you meet people who can help you, it puts some money in your pocket, and it helps to demonstrate a consistent work history. These are all great and important things both for finding your dream job, and also for battling your depression.